def to_timestamp(dt_str, tz_str):
    tz_utc= re.match(r'^UTC(.\d+):00',tz_str).group(1)
    # print(type(tz_utc), tz_utc)
    # str ==> datetime
    dt_datetime = datetime.strptime(dt_str,'%Y-%m-%d %H:%M:%S')
    # print(dt_datetime)
    # 创建指定时区tz_utc(提取自tz_str)
    tz_utc = timezone(timedelta(hours=int(tz_utc)))
    # 将给定时间dt_datetime(from dt_str)强制设置为指定的时区tz_utc
    dt_datetime_std = dt_datetime.replace(tzinfo=tz_utc)
    # 返回timestamp
    return dt_datetime_std.timestamp()